{"id":5,"date":"2023-03-26T16:50:01","date_gmt":"2023-03-26T20:50:01","guid":{"rendered":"https:\/\/nanoscience.ucf.edu\/hickman\/?page_id=5"},"modified":"2024-09-10T18:09:35","modified_gmt":"2024-09-10T22:09:35","slug":"home","status":"publish","type":"page","link":"https:\/\/nanoscience.ucf.edu\/hickman\/","title":{"rendered":"Home"},"content":{"rendered":"\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<!-- Bootstrap Carousel -->\n<div id=\"myCarousel\" class=\"carousel slide\" data-ride=\"carousel\">\n  \n  <!-- Indicators\/Dots -->\n  <ol class=\"carousel-indicators\">\n    <li data-target=\"#myCarousel\" data-slide-to=\"0\" class=\"active\"><\/li>\n    <li data-target=\"#myCarousel\" data-slide-to=\"1\"><\/li>\n    <li data-target=\"#myCarousel\" data-slide-to=\"2\"><\/li>\n    <li data-target=\"#myCarousel\" data-slide-to=\"3\"><\/li>\n    <li data-target=\"#myCarousel\" data-slide-to=\"4\"><\/li>\n    <li data-target=\"#myCarousel\" data-slide-to=\"5\"><\/li>\n    <li data-target=\"#myCarousel\" data-slide-to=\"6\"><\/li>\n    <li data-target=\"#myCarousel\" data-slide-to=\"7\"><\/li>\n  <\/ol>\n\n  <!-- Slideshow Wrapper -->\n  <div class=\"carousel-inner\">\n    \n    <!-- Slide 1 -->\n    <div class=\"carousel-item active\">\n      <img decoding=\"async\" src=\"https:\/\/gritcms.smca.ucf.edu\/wp-content\/uploads\/2024\/09\/cardiacmea.jpg\" class=\"d-block w-100\" alt=\"Cardiac MEA\">\n      <div class=\"carousel-caption d-none d-md-block\">\n        <h5>Cardiac cells on MEAs<\/h5>\n      <\/div>\n    <\/div>\n\n    <!-- Slide 2 -->\n    <div class=\"carousel-item\">\n      <img decoding=\"async\" src=\"https:\/\/gritcms.smca.ucf.edu\/wp-content\/uploads\/2024\/09\/cardiacstain.jpg\" class=\"d-block w-100\" alt=\"Cardiac Stain\">\n      <div class=\"carousel-caption d-none d-md-block\">\n        <h5>Patterned human cardiac cells stained for troponin (green) and actin (red)<\/h5>\n      <\/div>\n    <\/div>\n\n    <!-- Slide 3 -->\n    <div class=\"carousel-item\">\n      <img decoding=\"async\" src=\"https:\/\/gritcms.smca.ucf.edu\/wp-content\/uploads\/2024\/09\/huvec.jpg\" class=\"d-block w-100\" alt=\"HuVEC\">\n      <div class=\"carousel-caption d-none d-md-block\">\n        <h5>HuVEC 1 in HuVEC medium 14 DIV VE-Cad (green) CD31 (red) (40x maxpoint) 1<\/h5>\n      <\/div>\n    <\/div>\n\n    <!-- Slide 4 -->\n    <div class=\"carousel-item\">\n      <img decoding=\"async\" src=\"https:\/\/gritcms.smca.ucf.edu\/wp-content\/uploads\/2024\/09\/muscle.jpg\" class=\"d-block w-100\" alt=\"Human Muscle\">\n      <div class=\"carousel-caption d-none d-md-block\">\n        <h5>Human muscle and motoneurons<\/h5>\n      <\/div>\n    <\/div>\n\n    <!-- Slide 5 -->\n    <div class=\"carousel-item\">\n      <img decoding=\"async\" src=\"https:\/\/gritcms.smca.ucf.edu\/wp-content\/uploads\/2024\/09\/musclestain.jpg\" class=\"d-block w-100\" alt=\"Muscle Stain\">\n      <div class=\"carousel-caption d-none d-md-block\">\n        <h5>Human muscle and motoneurons stained for myosin heavy chain (green) and beta-III-tubulin (red)<\/h5>\n      <\/div>\n    <\/div>\n\n    <!-- Slide 6 -->\n    <div class=\"carousel-item\">\n      <img decoding=\"async\" src=\"https:\/\/gritcms.smca.ucf.edu\/wp-content\/uploads\/2024\/09\/motoneuronstain.jpg\" class=\"d-block w-100\" alt=\"Motoneuron Stain\">\n      <div class=\"carousel-caption d-none d-md-block\">\n        <h5>Human motoneurons stained for neurofilament (green) and beta-III-tubulin (red)<\/h5>\n      <\/div>\n    <\/div>\n\n    <!-- Slide 7 -->\n    <div class=\"carousel-item\">\n      <img decoding=\"async\" src=\"https:\/\/gritcms.smca.ucf.edu\/wp-content\/uploads\/2024\/09\/motoneuron.jpg\" class=\"d-block w-100\" alt=\"Motoneuron\">\n      <div class=\"carousel-caption d-none d-md-block\">\n        <h5>Human motoneurons (close up)<\/h5>\n      <\/div>\n    <\/div>\n\n    <!-- Slide 8 -->\n    <div class=\"carousel-item\">\n      <img decoding=\"async\" src=\"https:\/\/gritcms.smca.ucf.edu\/wp-content\/uploads\/2024\/09\/cardiacstain-1.jpg\" class=\"d-block w-100\" alt=\"Cardiac Stain\">\n      <div class=\"carousel-caption d-none d-md-block\">\n        <h5>Human cardiac cells stained for actin (red) and troponin (green)<\/h5>\n      <\/div>\n    <\/div>\n  <\/div>\n\n  <!-- Controls\/Arrows -->\n  <a class=\"carousel-control-prev\" href=\"#myCarousel\" role=\"button\" data-slide=\"prev\">\n    <span class=\"carousel-control-prev-icon\" aria-hidden=\"true\"><\/span>\n    <span class=\"sr-only\">Previous<\/span>\n  <\/a>\n  <a class=\"carousel-control-next\" href=\"#myCarousel\" role=\"button\" data-slide=\"next\">\n    <span class=\"carousel-control-next-icon\" aria-hidden=\"true\"><\/span>\n    <span class=\"sr-only\">Next<\/span>\n  <\/a>\n<\/div>\n\n<!-- Add Bootstrap CSS\/JS if not already included -->\n<link href=\"https:\/\/stackpath.bootstrapcdn.com\/bootstrap\/4.5.2\/css\/bootstrap.min.css\" rel=\"stylesheet\">\n<script src=\"https:\/\/code.jquery.com\/jquery-3.5.1.slim.min.js\"><\/script>\n<script src=\"https:\/\/cdn.jsdelivr.net\/npm\/@popperjs\/core@2.9.3\/dist\/umd\/popper.min.js\"><\/script>\n<script src=\"https:\/\/stackpath.bootstrapcdn.com\/bootstrap\/4.5.2\/js\/bootstrap.min.js\"><\/script>\n\n<!-- Custom CSS for Caption Background, Text Size, and Enhanced Arrows -->\n<style>\n  .carousel-caption {\n    \/* Remove the background color to get rid of the large dark grey box *\/\n    padding: 0; \/* Remove padding if needed *\/\n  }\n\n  .carousel-caption h5 {\n    background-color: rgba(211, 211, 211, 0.7); \/* Light grey background *\/\n    color: black; \/* Ensure the text is dark for contrast *\/\n    padding: 5px 10px;\n    display: inline-block;\n    border-radius: 5px; \/* Rounded corners *\/\n    font-size: 14px; \/* Smaller text size *\/\n  }\n\n  \/* Enhanced Arrows *\/\n  .carousel-control-prev,\n  .carousel-control-next {\n    width: 5%; \/* Increase the width for better visibility *\/\n  }\n\n  .carousel-control-prev-icon,\n  .carousel-control-next-icon {\n    background-color: rgba(0, 0, 0, 0.5); \/* Dark background behind the arrows *\/\n    border-radius: 50%; \/* Round background *\/\n    padding: 10px; \/* Add padding around the arrow icon *\/\n    background-size: 100%, 100%; \/* Scale the background *\/\n  }\n\n  .carousel-control-prev-icon::before,\n  .carousel-control-next-icon::before {\n    font-size: 24px; \/* Increase the size of the arrows *\/\n    color: white; \/* Change arrow color to white for better contrast *\/\n  }\n<\/style>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-video\"><video height=\"268\" style=\"aspect-ratio: 478 \/ 268;\" width=\"478\" controls src=\"https:\/\/nanoscience.ucf.edu\/wp-content\/uploads\/sites\/18\/2023\/03\/hickman-intro-full.webm\"><\/video><\/figure>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading h4 heading-underline mt-4 mt-lg-5\" id=\"h-mission\">Mission<\/h2>\n\n\n\n<p class=\"font-slab-serif lead\">Engineering the interface between biological and non-biological systems to construct next-generation systems for toxicology, drug discovery, and basic biology research.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading h4 heading-underline mt-4 mt-lg-5\" id=\"h-featured-topics\">Featured Topics<\/h2>\n\n\n\n<div id=\"accordion\" role=\"tablist\">\n  <div class=\"card\">\n    <div class=\"card-header\" role=\"tab\" id=\"topicOne\">\n      <h3 class=\"h5 mb-0\">\n        <a class=\"text-decoration-none text-secondary\" data-toggle=\"collapse\" href=\"#collapseOne\" aria-expanded=\"false\" aria-controls=\"collapseOne\">\n          Dr. Hickman and Dr. Shuler of Cornell Awarded 2015 Lush Prize\n        <\/a>\n      <\/h3>\n    <\/div>\n    <div id=\"collapseOne\" class=\"collapse\" role=\"tabpanel\" aria-labelledby=\"topicOne\" data-parent=\"#accordion\">\n      <div class=\"card-block\">\n        Body-on-chip technology developed by UCF and Cornell University scientists has been awarded a major international prize for its capability to test pharmaceuticals without using animal subjects. This innovative technology, also known as Human-on-a-Chip, was recently awarded the <strong>2015 Lush Prize for Science<\/strong> over 11 finalists from Japan, Switzerland, Germany, South Korea, Australia, the U.K. and the U.S.\n      <\/div>\n    <\/div>\n  <\/div>\n  <div class=\"card\">\n    <div class=\"card-header\" role=\"tab\" id=\"topicTwo\">\n      <h3 class=\"h5 mb-0\">\n        <a class=\"collapsed text-decoration-none text-secondary\" data-toggle=\"collapse\" href=\"#collapseTwo\" aria-expanded=\"false\" aria-controls=\"collapseTwo\">\n          Hickman laboratory to be featured by PBS Affiliate\n        <\/a>\n      <\/h3>\n    <\/div>\n    <div id=\"collapseTwo\" class=\"collapse\" role=\"tabpanel\" aria-labelledby=\"topicTwo\" data-parent=\"#accordion\">\n      <div class=\"card-block\">\n        The Hickman lab is currently collaborating with Stephanie Rice and the UCF Nicholson School of Communication to produce a documentary piece to air on PBS. The documentary will serve to highlight the cutting edge research currently underway at the Hybrid Systems Lab and the implications this research will have on drug development in the near future.\n      <\/div>\n    <\/div>\n  <\/div>\n  <div class=\"card\">\n    <div class=\"card-header\" role=\"tab\" id=\"topicThree\">\n      <h3 class=\"h5 mb-0\">\n        <a class=\"collapsed text-decoration-none text-secondary\" data-toggle=\"collapse\" href=\"#collapseThree\" aria-expanded=\"false\" aria-controls=\"collapseThree\">\n          JoVE comes to UCF\n        <\/a>\n      <\/h3>\n    <\/div>\n    <div id=\"collapseThree\" class=\"collapse\" role=\"tabpanel\" aria-labelledby=\"topicThree\" data-parent=\"#accordion\">\n      <div class=\"card-block\">\n        The <em>Journal of Visualized Experiments<\/em> will be coming to the Hybrid Systems Lab in May to film content for an article highlighting the patented cantilever technology employed by UCF researchers to investigate the contractile properties of cultured human muscle cells. This article will provide in depth instruction on how to use the cantilever system to scan cultures for contractile activity and how to perform analysis on the collected data to identify differences between treatment groups.\n      <\/div>\n    <\/div>\n  <\/div>\n  <div class=\"card\">\n    <div class=\"card-header\" role=\"tab\" id=\"topicFour\">\n      <h3 class=\"h5 mb-0\">\n        <a class=\"collapsed text-decoration-none text-secondary\" data-toggle=\"collapse\" href=\"#collapseFour\" aria-expanded=\"false\" aria-controls=\"collapseFour\">\n          Hickman research featured in <em>Advances in Engineering<\/em>\n        <\/a>\n      <\/h3>\n    <\/div>\n    <div id=\"collapseFour\" class=\"collapse\" role=\"tabpanel\" aria-labelledby=\"topicFour\" data-parent=\"#accordion\">\n      <div class=\"card-block\">\n        <p>The recent paper \u201cCorrelation of embryonic skeletal muscle myotube physical characteristics with contractile force generation on an atomic force microscope-based bio-microelectromechanical systems device\u201d has been featured in <a href=\"http:\/\/advanceseng.com\/applied-physics\/correlation-embryonic-skeletal-muscle-myotube-physical-characteristics-contractile-force-generation-atomic-force-microscope-based-bio-microelectromechanical-systems-device\/\" target=\"_blank\" rel=\"noopener\"><em>Advances in Engineering<\/em><\/a>. The <em>Advances in Engineering<\/em> readership includes Engineering industry, universities, colleagues, research institutions, and libraries and is dedicated to providing a forum for free and open exchanges of ideas, information, and experiences concerning scientific matters. To meet this objective, the activities of <em>Advances in Engineering<\/em> include publishing subjects of interest with special focus on key published scientific articles, promising technologies, top patents and licensing opportunities, top events and conferences in all Engineering disciplines. We are very happy to have our work featured in such an important scientific forum.<\/p>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading h4 heading-underline mt-4 mt-lg-5\" id=\"h-events\">Events<\/h2>\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-february-19-2022\">February 19, 2022<\/h5>\n\n\n\n<p><a href=\"https:\/\/med.ucf.edu\/mdna\/the-central-florida-brain-bee\/\" target=\"_blank\" rel=\"noreferrer noopener\">Central FL Brain Bee, UCF<\/a><\/p>\n\n\n\n<hr class=\"hr-1\">\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-april-16-17-2022\">April 16 &#8211; 17, 2022<\/h5>\n\n\n\n<p><a href=\"https:\/\/www.eng.ufl.edu\/nimet\/events\/nanoflorida-conference\/nanoflorida-2022\/\" target=\"_blank\" rel=\"noreferrer noopener\">NanoFlorida, UF<\/a><\/p>\n\n\n\n<hr class=\"hr-1\">\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-april-21-22-2022\">April 21 &#8211; 22, 2022<\/h5>\n\n\n\n<p><a href=\"https:\/\/waset.org\/recent-advances-in-artificial-organ-engineering-conference-in-april-2022-in-london\" target=\"_blank\" rel=\"noreferrer noopener\">Organ Modeling Congress, London, UK<\/a><\/p>\n\n\n\n<hr class=\"hr-1\">\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-april-27-30-2022\">April 27 \u2013 30, 2022<\/h5>\n\n\n\n<p><a href=\"https:\/\/biomaterials.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">Society for Biomaterials, Baltimore<\/a><\/p>\n\n\n\n<hr class=\"hr-1\">\n\n\n\n<h5 class=\"wp-block-heading\" id=\"h-may-27-june-3-2022\">May 27 \u2013 June 3, 2022<\/h5>\n\n\n\n<p><a href=\"https:\/\/mpsworldsummit.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">MPS-WS, New Orleans, LA<\/a><\/p>\n\n\n\n<hr class=\"hr-1\">\n\n\n\n<p><a href=\"https:\/\/nanoscience.ucf.edu\/hickman\/events\/\" data-type=\"page\" data-id=\"235\" target=\"_blank\" rel=\"noreferrer noopener\">See the Full List of Events<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"Cardiac cells on MEAs Patterned human cardiac cells stained for troponin (green) and actin (red) HuVEC 1 in HuVEC medium 14 DIV VE-Cad (green) CD31 (red) (40x maxpoint) 1 Human muscle and motoneurons Human muscle and motoneurons stained for myosin heavy chain (green) and beta-III-tubulin (red) Human motoneurons stained for neurofilament (green) and beta-III-tubulin (red)&hellip;","protected":false},"author":69,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.0 (Yoast SEO v26.9) - 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