Sep 2021: Prof. Rajaraman was recently elected to a leadership position in the MEMS/Sensors/Transducers Community as a Member of the Board of Directors of Transducers Research Foundation charged with the mission to stimulate research in science and engineering, with emphasis on technologies related to transducers, microsystems, and nanosystems, and to foster the exchange of ideas and information between academic, industrial, and government researchers. For more info, please visit: https://www.transducer-research-foundation.org/discover_TRF/officers_and_directors.html       •       Aug 2021: Prof. Rajaraman is co-organizing and co-hosting an online mini-symposium on bioelectronics for pain and addiction. For more information and registering to attend the symposium for free, please visit: https://mistcenter.org/meeting/ultimate/bioelectronics/       •       July 2021: Nilab graduated with her Ph.D. in Chemistry, successfully defending her Ph.D. on July 1, 2021. Congrats Dr. Azim!       •       June 2021: Our work on “Tri-Modal 3D MEAs" won the Best Poster Award at the recently concluded virtual meeting, IEEE Transducers 2021. For more info please visit: https://transducers2021.org/home/award_winners.html       •       June 2021: The NanoBioSensors and Systems Group welcomes a new undergraduate students - Jennifer Nguyen, B.S. student in Mechanical Engineering and Rhondra Giscombe, B.S. student in Materials Science & Engineering. Welcome Jennifer and Rhondra!       •       May 2021: The Rajaraman Group welcomes a new student to the group: Omar Cepeda Torres, NSF REU student joins us for summer 2021 from Polytechnic University of Puerto Rico. Welcome Omar!       •       April 2021: The group’s first journal paper with a high school student as the first author will be published in the Journal of Young Investigators. Here’s an early press release about it: https://www.jyi.org/2021-may/2021/5/1/press-release-microneedles-to-help-overcome-a-major-citrus-crop-disease       •       March 2021: Our review paper on 2D and 3D MEAs was chosen among a select few articles in IoP JMM as “Highlights of 2020”: https://iopscience.iop.org/journal/0960-1317/page/highlights-of-2020       •       Feb 2021: The NanoBioSensors and Systems Group welcomes a new undergraduate student - Aliyah Baksh a B.S. student in Biology. Welcome Aliyah!       •       January 2021: We start the Spring 2021 semester still under COVID restrictions. The NanoBioSensors and Systems Group welcomes a new graduate student - Andre Childs, a Ph.D. student in Materials Science and Engineering. Welcome Andre!       •       December 2020: Two of the three submitted papers from the group got accepted to MEMS 2021 including a paper for Oral Presentation. For more information on the program, please visit: https://www.mems21.org/program/MEMS2021_Program.pdf       •       November 2020: Cacie graduated with her Ph.D. in Materials Science and Engineering, successfully defending her Ph.D. on Nov. 20, 2020. Congrats Dr. Hart!       •       October 2020: Prof. Rajaraman will attend BioFlorida 2020 held virtually. For more information, please visit: https://biofloridaconference.pathable.co/agenda       •       September 2020: Prof. Rajaraman is part of the organizing committee for the North American Materials Colloquium Series (NAMCS) promoting top Materials researchers across North America. For more details please visit: http://namcs.org       •       September 2020: Prof. Rajaraman is giving an invited talk at the annual IEEE NEMS Meeting on Impedance-based Biosensors. For more details please visit: https://ieee-nems.org/2020/       •       August 2020 We start a Fall semester unlike any other. The NanoBioSensors and Systems Group welcomes a new graduate student - Jorge Manrique Castro, a Ph.D. student in Electrical Engineering. Welcome Jorge!       •       July 2020: Five of the Seven (5/7) papers the NanoBioSensors & Systems Group submitted to the special issue of IEEE JMEMS for Hilton Head 2020 were accepted and are available online: https://ieeexplore.ieee.org/xpl/tocresult.jsp?isnumber=4357932       •       June 2020: Research Labs around UCF are beginning to slowly open following university guidelines: https://corona.research.ucf.edu. The NanoBioSensors and Systems Lab is open currently.       •       May 2020: Dr. Rajaraman presented at the inaugural UCF CECS Virtual Faculty Seminar Series. The title of his talk was "Makerspace Micro/Nanofabrication of Biomedical and Agricultural MicroSystems".       •       March 2020 - May 2020: The NanoBioSensors and Systems Lab was closed due to the COVID-19 Pandemic.       •       February 2020: Both of our submitted abstracts were accepted (57% acceptance rate) for poster presentation at the Hilton Head MEMS Meeting 2020. For more details on the terrific program, please visit: https://www.hh2020.org       •       February 2020: For the third year in a row, Laboni Santra a 11th grade student from Oviedo High School and a volunteer in the lab won multiple awards at the Seminole County Science, Math and Engineering Fair held on February 6, 2020. Laboni won: 1st place in Plant Sciences category and Special awards from the U.S. Metric Association and the Yale Science and Engineering Association, including Nomination to Florida State Science and Engineering Fair and Nomination to Regeneron International Science and Engineering Fair in Anaheim, California. Incredible accomplishment for three years straight! Carry on this tremendous success Laboni! Congratulations!       •       January 2020: Dr. Rajaraman will attend the IEEE MEMS 2020 (https://www.mems20.org) and present one poster on DLP 3D Printing of High Aspect Ratio structures from the group.       •       January 2020: Happy New Year! The NanoBioSensors and Systems Group welcomes a new graduate student - Julia Freitas Orrico, a masters student in Nanotechnology. Welcome Julia!       •       November 2019: Dr. Rajaraman, Avra, Khalid, Chuck, Paola and Laboni will attend NanoFlorida 2019 to present 2 talks and one poster. For more details, please visit: https://www.nanoflo.org       •       October 2019 Dr. Rajaraman attended the 15th Tissue Chips Consortium Meeting in Washington, DC. For more information on the meeting, please visit: https://www.eventbrite.com/e/15th-nih-tissue-chip-consortium-meeting-registration-65125708748       •       September 2019: Dr. Syed Khalid Pasha joined the group as a post-doctoral fellow. Welcome Khalid!       •       August 2019: Dr. Rajaraman attended the Nordic Organ on a Chip Meeting in Tampere, Finland and gave an invited talk at the meeting on the development of 2D and 3D Microelectrode Arrays. For more information on the meeting, please visit: https://events.tuni.fi/nooc2019/       •       August 2019: The Rajaraman Group welcomes a new volunteer, Nicholas Alban a sophomore in ECE. Welcome Nick!       •       July 2019: Chuck successfully defended his M.S. thesis on July 3, 2019. His thesis is entitled: DEVELOPMENT OF 3D PRINTED AND 3D METAL-BASED MICRO/NANOFABRICATED, AND NANO-FUNCTIONALIZED, MICROELECTRODE ARRAY (MEA) BIOSENSORS FOR FLEXIBLE, CONFORMABLE, AND IN VITRO APPLICATIONS. Congrats Chuck! He starts his Ph.D. at UCF in Fall 2019.       •       June 2019: Chuck and Dr. Rajaraman attend the Transducers-Eurosensors 2019 Meeting (https://transducer s-eurosensors2019.org) and present 2 posters from the group.       •       June 2019: The Rajaraman Group welcomes new students to the group: Paola Morales Carvajal, NSF REU student joins us for summer 2019 from Polytechnic University of Puerto Rico and Parker Arnett, junior in Mechanical Engineering joins the group as a volunteer. Welcome Paola and Parker!       •       May 2019: New paper from the group is published in IEEE JMEMS. Please see the link for details and downloading options: https://ieeexplore.ieee.org/document/8709727       •       May 2019: Rajaraman Group students have won several awards and fellowships: Charles Didier was awarded the ORCGS Doctoral Fellowship for Ph.D. studies starting Fall 2019. This university fellowship was created by the Office of Research and College of Graduate Studies to be awarded to outstanding incoming doctoral students who have demonstrated excellent academic achievement, preparation, and potential for successful graduate study at UCF. Congrats Chuck!; Cacie Hart won a Doctoral Research Support Award from the College of Graduate Studies. Congrats Cacie!; Julia Orrico won a Office of Undergraduate Research Student Research Grant. Congrats Julia!       •       April 2019: Laboni’s project entitled “A Minimally-Invasive 3D-Printed Microneedle Array Applicator System (µNAAS) for Delivery of Therapeutics to Citrus Leaf Tissue” won First Place in the 64th State Science and Engineering Fair of Florida in the area of Plant Sciences. Laboni’s project was also selected as a Finalist (top 5 in all of Central Florida) for the Dr. Nelson Ying Award. Laboni will present for this award a compete for the top prize at the end of April 2019. Congratulations Laboni on such amazing accomplishments.       •       March 2019: New paper from the group is published in RSC Advances. Please see the link for details and downloading options: https://pubs.rsc.org/en/content/articlelanding/2019/ra/c8ra09116a#!divAbstract       •       Both of our submitted abstracts were accepted (44% acceptance rate) for poster presentation at the IEEE Transducers-Eurosensors 2019. For more details, please visit: https://transducers-eurosensors2019.org       •       February 2019: Laboni Santra, a 10th grade student from Oviedo High School and a volunteer in the lab won multiple awards for the second year running at the Seminole County Science, Math and Engineering Fair held on February 2, 2019. Laboni won - 1st place Plant Sciences Category, Nominee for State Science and Engineering Fair of Florida, Best of Show, 1st Alternate for the Intel International Science and Engineering Fair - An amazing accomplishment for two straight years. Congratulations Laboni!       •       February 2019: Adam Rozman, a freshman in Mechanical Engineering joined the lab as a volunteer. Welcome Adam!       •       January 2019: Happy New Year! The NanoBioSensors and Systems Group welcomes a new graduate student (co-advised with Prof. Tetard, NSTC and Department of Physics) - Miguel Tirado, a masters student in Nanotechnology. Welcome Miguel!       •       January 2019: New papers from the group are published in Biosensors and IEEE JMEMS. Biosensors paper link: https://www.mdpi.com/2079-6374/8/4/88 IEEE JMEMS paper link: https://ieeexplore.ieee.org/document/8604145       •       November 2018: Cacie, Chuck and Dr. Rajaraman attend the MicroTAS 2018 Meeting and present 2 posters from the group. Both Cacie and Chuck won travel awards to attend the meeting, from NSTC (UCF), Student Government Association (UCF), College of Graduate Studies (UCF) and from the organizing committee of MicroTAS, the Chemical & Biological Microsystems Society (CBMS). Congrats Cacie and Chuck!       •       November 2018: Dr. Rajaraman was invited to give a talk at the Third Annual Materials Innovation in Sustainable Agriculture (MISA) Symposium. For more details, please visit: http://nanoscience.ucf.edu/misa/symposium.php       •       October 2018: Dr. Rajaraman, Avra, Crystal and Laboni will attend NanoFlorida 2018 to present 3 posters and one invited talk. For more details, please visit: http://411.fit.edu/nanoflorida/       •       October 2018: Dr. Rajaraman gave the ECE Seminar at Georgia Tech on Oct 3, 2018.       •       September 2018: Darina Khater joins the group as an undergraduate volunteer. Welcome Darina!       •       August 2018: Dr. Rajaraman was featured and interviewed on the Nanovation Podcast. For more details and to listen to the Podcast, please visit: http://www.fillerlab.com/nanovation/archive/40       •       July 2018: Two of our abstracts were accepted for poster presentation at the MicroTAS 2018 Meeting.       •       July 2018: Two of our abstracts to the MEA 2018 Meeting were accepted and Sarah & Sandra attend the meeting to present the work.       •       June 2018: Nilab, Avra and Dr. Rajaraman attend the Hilton Head MEMS 2018 Meeting and present 2 posters from the group. Nilab won two travel awards to attend the meeting, one from NSTC (UCF) and another from the Transducers Research Foundation. Congrats Nilab!       •       May 2018: Ms. Crystal Nattoo from the University of Miami joins the group as a NSF Research Experience Undergraduate (REU) scholar. Welcome Crystal!

Introduction

The natural applicability of micro and nano-scale technologies in life sciences, agriculture and associated areas opens new avenues for powerful interdisciplinary collaboration between scientists, engineers and medical professionals. The goal of our research group is the development of new micro/nanofabrication technologies and associated packaging technologies to address applications that advance the state of the art in human health. We develop both traditional (silicon and glass based) and non-traditional (Polymers, Metal, Paper, Biomaterials etc.) micro/nanofabrication methodologies and focus on the applications of these technologies in cell-based assays outside the body, diagnostic & therapeutic systems in plants and biology and other novel applications. Our focus will be on the non-traditional and bio-friendly fabrication methodologies but based on a particular project we will choose the best technique that addresses a particular application.

We collaborate with scientists and engineers in the areas of biotechnology, toxicology, pharmacology, microfluidics, genomics, proteomics, diagnostics, therapeutics, plant sciences and medical devices that can advance the goals of the group and guide the applications of the platform technologies that our group develops.

See more details of a brief group introduction by Prof. Rajaraman in the CECS virtual seminar in May 2020: https://youtu.be/w71IWcwoiWw

Card image cap
Dr. Swaminathan Rajaraman
Assistant Professor & Principal Investigator
Primary Affiliations

NSTC, Department of Materials Science & Engineering.

Secondary Affiliations

Department of Electrical & Computer Engineering, Burnett School of Biomedical Sciences

Major Research Areas

Engineering the "Organ on a Chip" Revolution

"Organs on a Chip" or Microphysiological Systems (MPS) have been identified as promising candidates for improved preclinical models of various organs and the interplay between these organs. Engineering interfaces to these MPS requires a multidisciplinary understanding encompassing micro/nanoengineering, electrical stimulation/recording, microfluidic flow, biocompatibility, materials science, optics etc. Our research group specializes in the development of such interfaces working closely with collaborators at UCF, Tulane University, University of Wisconsin (Madison), private companies and other entities.

Responsive image
Responsive image

Diagnostic and Therapeutic Micro/NanoSystems for Biology and Plants:

Makerspace Micro/Nanofabrication technologies are ideally suited for the next generation of diagnostic and therapeutic micro/nanosystems as these technologies can rapidly integrate processes for the creation of prototypes for several applications: for instance for the efficient delivery of agrochemicals, such as fertilizers and pesticides to plants, one of the key elements for improved food productivity and security; or monitoring dehydration in the human body or developing Point of Care (POC) diagnostic systems. In collaboration with other groups at UCF, UF, JHU, FAMU, private companies and other entities, our research group works on the development of novel diagnostic and therapeutic microsystems.

Micro/NanoEngineering in other Novel Applications:

The applications of micro/nanoengineering continue to grow slowly encroaching areas and fields one would not have dreamt of say even a decade ago. We are always interested in exploring the theoretical background behind many new Makerspace Micro/Nanofabrication technologies such as Digital Light Processing (DLP) 3D Printing or evaluating the best microfabrication technology for a particular application. This research is performed in the group mostly in collaboration with UCF researchers, private companies and other entities

Responsive image