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Dr. Swaminathan Rajaraman

Associate Professor & Principal Investigator

Primary Affiliations

NSTC, Department of Materials Science & Engineering

Secondary Affiliations

Department of Electrical & Computer Engineering, Burnett School of Biomedical Sciences

Principal Investigator

Swaminathan Rajaraman received his B.S. degree in Electronics Engineering from Bharathidasan University (Trichy, India), his M.S. degree in Electrical Engineering (specialization: Semiconductors and Micro/NanoEngineering) from the University of Cincinnati (Cincinnati, OH) and his Ph.D. degree in Electrical Engineering (specialization: Neuroscience and Micro/NanoEngineering) from the Georgia Institute of Technology (Atlanta, GA) respectively.

Prof. Rajaraman is an academic and a successful entrepreneur. He is currently Associate Professor in the NanoScience Technology Center and the Department of Materials Science and Engineering at the University of Central Florida (Orlando, FL). He has secondary joint appointments in the Department of Electrical and Computer Engineering and the Burnett School of Biomedical Sciences at the University of Central Florida (Orlando, FL). He runs a very interdisciplinary group composed on Electrical Engineers, Biomedical Scientists, Material Scientists, Mechanical Engineers, and Chemists. His current research interests include in vitro and in vivo Microelectrode Arrays (MEAs), micro/nanofabrication, micro/nanofabrication on novel, biological substrates, hybrid biosystems, microneedles, agricultural microsystems, microfluidic devices, multimodal cell-based nanosensors, 3D printing and implantable MEMS devices. He also serves as the Deputy Director of the NSF I/UCRC, MIST Center (https://mistcenter.org) at UCF.

Prior to his academic appointment, he has worked in the Micro-Electro-Mechanical Systems (MEMS) industry with Analog Devices Inc., (Cambridge, MA), a world-leader in MEMS manufacturing and CardioMEMS (now Abbott Labs, Atlanta, GA) which developed the world’s first FDA approved implantable MEMS pressure sensor. Dr. Rajaraman worked on developing MEMS micromirrors and implantable MEMS pressure sensors respectively at Analog and CardioMEMS. He further co-founded Axion BioSystems Inc. (https://www.axionbiosystems.com Atlanta, GA), a world-leader in high-throughput Microelectrode Arrays and MEA systems. Axion raised more than $30 Million in non-dilutive and venture funding and employs more than 100 people worldwide with revenues of several million every year. All the five (5) products he has developed to date at Axion are in volume production. These high-throughput Microelectrode Arrays products have been used more than 6.25 million experiments worldwide in over 250 sites as of 2021. In July 2021, Axion was successfully acquired by the Swedish Private Equity Firm, Summa Equity (https://www.axionbiosystems.com/resources/product-brochure/summa-equity-acquires-axion-biosystems) for in excess of $100 Million. Axion spin out, BioCircuit Technologies was recently awarded an FDA 510K approval for selling one of their implantable products (https://www.biocircuit.com) and raised close to $9 Million recently in seed funding. In December 2020, he co-founded his second company, Primordia BioSystems Inc. (https://primordia-biosystems.com) to commercialize concepts from his UCF research group.

He has published more than 80 articles in peer-reviewed journals and conferences and holds in excess of 30 patents and applications. So far, he has raised more than to $12 Million in funding for his research and product development activities at Axion, Primordia and at UCF. He has additionally mentored close to 50 graduate students, undergraduate students, engineers and post-doctoral fellows.

Dr. Rajaraman was the Track Chair for a Bioelectric Sensors session in IEEE Engineering in Medicine and Biology Conference (EMBC) 2010, a Session Co-Chair at NanoFlorida 2018 & 2019, a Session Co-Chair for IEEE MEMS Conference 2020, and a Session Chair at IEEE MEMS Conference 2021. He has served/serves on the Technical Program Committee (TPC) of the Solid State Sensors, Actuators and Microsystems Workshop (Hilton Head 2014, 2016 and 2022) and will be the Technical Program Chair for the Hilton Head meeting in 2024, IEEE Transducers 2021, 2023, IEEE MEMS 2022 and served as the Vice Chair for Commercial Development at the Hilton Head 2020 meeting and Chair of Commercial Development for the Hilton Head 2022 meeting (his committee has raised close to $160,000 for this meeting). Further, he has served on the TPC of IEEE Sensors Conference in 2016 and 2017. He was also one of the five organizers of the North American Materials Colloquium Series (namcs.org), a novel virtual seminar series on new materials research across 36 universities to promote post-docs and senior Ph.D. students attracting 500+ attendees weekly. He further co-organized an International Virtual Symposium on Bioelectronics for Pain and Addiction (https://mistcenter.org/meeting/ultimate/bioelectronics/) in 2021. He was also elected to the Transducers Research Foundation (https://www.transducer-research-foundation.org) Board of Directors in 2021. He also chairs the hiring of multiple faculty lines currently at UCF focused on infectious diseases, materials, sensors, and health technologies. He has reviewed papers for numerous journals in MEMS, Microfluidics, Neuroscience, Biomedical Engineering, Materials Science, Optics, and other disciplines. He regularly reviews proposals for the NSF, NIH POCTRN, internal UCF proposals, ZonMW Netherlands healthcare funding agency and Oak Ridge Affiliated Universities Powe Award funding opportunities. Since 2019, he serves on the Editorial Board of Nature Scientific Reports and since 2022, on the Editorial Board of IEEE JMEMS. Additionally, Dr. Rajaraman recently joined the Scientific Advisory Board of World Precision Instruments (https://www.wpiinc.com)

Current Team Members

Charles Didier, Ph.D.
Visiting Researcher

Affiliations
NSTC, Burnett School of Biomedical Sciences

Charles.Didier@ucf.edu

Education:
B.S. Biomedical Sciences, UCF, 2015
B.S. Biotechnology, UCF, 2015
M.S. Nanotechnology, UCF, 2019
Ph.D. Biomedical Sciences, 2022

Background & Interests: Chuck is looking to research how variants in 3D MEA technology can be applied to implants for Prosthetic signaling applications. Always a student of the sciences, he has been guided towards Prosthetics from an early age where he learned of his cousins need for a lower limb prosthetic (provided by Ottobock). His interest in Biology and Medicine throughout his Undergraduate career led him to the Nanoscience Technology Center at UCF where he hopes to begin research and development on neural Implant devices to bridge the gap between traditional and advanced prosthetic devices, and the human body. He hopes to pursue his PhD in the future within the field of Biomedical Engineering, with an emphasis on Nanotechnology and its applications in the industry.

Monisha Elumalai, Ph.D.
Post Doctoral Scholar
Monisha.Elumalai@ucf.edu

Education:
B.E. Electronics and Communication Engineering, Ganadipathy Tulsi’s Engineering College
(Anna University affiliated), India, 2012

M.Tech. Sensor System Technology, Vellore Institute of Technology (VIT) University, India, 2016

Ph.D. Science and Technology in colloids and interfaces, University of Vigo (Uvigo), Spain and International Iberian Nanotechnology Laboratory (INL), Portugal, 2021

Postdoctoral research scholar, Purdue University, USA, 2023

Background & Interests: Monisha has gained hands-on experience in various aspects of nanotechnology, including nanoparticle synthesis and characterization studies using techniques like UV-vis spectroscopy, Dynamic Light Scattering measurements (DLS), and Transmission Electron Microscopy (TEM). She has also demonstrated expertise in functionalizing DNA or antibodies onto gold nanoparticles. Her diverse skill set extends to the development of lateral flow devices, optical DNA biosensors integrated into automated microfluidic systems, implementation of DNA amplification techniques, exploration of protein-antibody interaction studies, antibody screening using biolayerinterferometry (BLI), and a comprehensive understanding of gas sensors.

Currently at University of Central Florida (UCF), Monisha’s work will be focusing on 3D microelectrode arrays (MEA) and will be involving in integration and testing of piezoresistive sensors on a shoe insole for diabetic neuropathy applications.

Surbhi Tidke
B.E., M. Tech
Ph.D. student

Surbhi.Tidke@ucf.edu

Education:
B.E. Biomedical Engineering, Mumbai University, India 2014

M.Tech Electrical Engineering, Vellore Institute of Technology (VIT) Vellore, India 2016

Ph.D. Electrical Engineering, University of Central Florida (UCF)

Background & Interests: 

Surbhi has more than 3 years of research experience. Her expertise is in the realm of optoelectronic nanophotonic plasmonic devices extending to both modulation and biosensing applications, complemented by crafting nanostructures using nanofabrication techniques and simulation tools like COMSOL, TCAD, Lumerical, and Matlab. Notably, she recently contributed her skills at Temasek Laboratories (TL) at Nanyang Technological University (NTU) Singapore. Her work at NTU encompassed the intricate fabrication and measurements of DC/Pulse I-V, C-V, and S-parameter using an on-chip vector network analyzer (VNA) of 40GHz for mmWave devices like HEMT, CMOS, and TFET. 

Currently, Surbhi is diligently bringing her diverse electrical and biomedical engineering expertise to develop an optimized product for the healthcare industry.

Omar S. Cepeda Torres
Ph.D. student in Biomedical Engineering

Affiliations
NSTC, BME

Omar.CepedaTorres@ucf.edu

Education:
B.S. Biomedical Engineering, Polytechnic University of Puerto Rico, 2022.
M.S. Nanotechnology, University of Central Florida, 2024.

Ph.D. Biomedical Engineering, University of Central Florida.
Background & Interests: Omar started to evolve as a researcher in 2019 at the Polytechnic University of Puerto Rico’s Plasma Laboratory in where the focus of the research was to develop a sterilization method using air as ionized gas (air in plasma state) by the Glow Discharge method. During the summer of 2021, Omar had the opportunity to be part of the University of Central Florida’s National Science Foundation Research Experiences for Undergraduates (REU) on Engineering and Nanoscience of Materials and Device Applications in Biotechnology and Medicine. At Dr. Rajaraman’s NanoBiosensors & Systems Group, Omar research objective was to create a Penta-Modal biosensor platform, which incorporates a transparent polymer substrate (for cellular image analysis), stainless steel (SS) 3D microelectrode array (3D MEA) structures, with an included 3D microfluidic adaptation, and both temperature and analyte sensing capabilities all on a single chip. Omar discovered through presenting his work that he can continue to incorporate engineering into devices to improve medical treatments, which has always been a passion of him. He desires to further his academic development in order to seek a career in science with medicine

Randall James
M.S. Thesis Student in Biotechnology

Affiliations
NSTC, BME

Randall.James@ucf.edu

Education:
B.S., University of Central Florida, Biomedical Sciences

Background & Interests: Randall’s previous research experience was obtained at the Burnett School of Biomedical Sciences, in the field of neuroscience. His primary interest is in developing Micro-electrode Arrays and Cellular Biosensors to improve models of diseases of the central nervous system. Randall is interested in investigating the bioenergetics of aging and characterizing metabolism throughout disease progression. After completion of the M.S. in Biotechnology, Randall intends to pursue an M.D./M.S. in Biomedical Engineering.

Diana Rodriguez de Francisco
Graduate Research Assistant

Affiliations
BME, NSTC

diana.rodriguezdefrancisco@ucf.edu

Education:
B.S. Mechanical Engineering, Metropolitan University, Caracas, Venezuela, 2023

M.S. Biomedical Engineering, University of Central Florida.

Background & Interests:  Diana started involved in research in 2021 when she decided to focus her undergraduate thesis on the hemodynamic validation of a flow diverter for intracranial aneurysms. Afterward, she worked designing an external late cranioplasty prototype for LMIC that won the Best in Business Award at the Bench to Bedside competition in 2023. Currently serving as a Computer-Aided Design professor at Metropolitan University. Previously, worked as a teaching assistant in the Fluid Mechanics Laboratory and the Programming course. Possesses expertise in various software tools including AutoCAD, CFD, and Inventor. She is also involved in research projects at Metropolitan University, including designing an aortic stent and serving as a thesis advisor for mechanical engineering students. At Dr. Rajaraman’s NanoBiosensors & Systems group, her objective is to develop a microneedle patch for drug delivery. 

Ji Chang
Ph.D. student in Biomedical Sciences

Affiliations
NSTC (Co-Advised with Prof. Laurene Tetard)

ji774529@ucf.edu

Education:
B.S. Biomedical Sciences, University of Central Florida 2021

M.S. Nanotechnology, University of Central Florida, 2024.

Ph.D. Biomedical Sciences, University of Central Florida.

Maria Tregansin
Undergraduate Research Assistant

Affiliations
Department of Mechanical and Aerospace Engineering, NSTC

mariatregansin@ucf.edu

Nadav Shanun
Undergraduate Research Assistant

Affiliations
Department of Electrical and Computer Engineering, NSTC

na195633@ucf.edu

Tatiana Hostios
Undergraduate Research Assistant

Affiliations
Burnett School of Biomedical Sciences, NSTC

ta617552@ucf.edu

Blake Walker
Undergraduate Research Assistant

Affiliations
Department of Electrical and Computer Engineering, NSTC

Bwalk@ucf.edu

UCF Alumni of NBSS Group

Ph.D. Graduates

  1. Dr. Andre Childs (2021-2024): Andre is currently a post-doctoral scholar at Rice University in Houston, Texas.
  2. Dr. Jorge Manrique Castro (2020 – 2023): Jorge is currently Assistant Professor in ECE Department at University of Texas at El Paso (UTEP) in El Paso, Texas.
  3. Dr. Charles Didier (2019 – 2022): Chuck is currently a Sensor Development Manager at Orthomerica in Orlando, FL.
  4. Dr. Nilab Azim (2016 – 2021): Nilab is currently a Research Engineer at NASA in Cape Canaveral, FL
  5. Dr. Cacie Hart (2017 – 2020): Cacie is currently an Engineering Manager at Alleima in Palm Coast, FL.

M.S. Thesis Graduates

  1. Mr. Omar S. Cepeda Torres (2024); continuing research in the NBSS Group as a Ph.D. student in Biomedical Sciences, UCF.
  2. Ms. Ji Chang (2024); continuing research in the NBSS Group as a Ph.D. student in Biomedical Sciences, UCF.
  3. Mr. Pablo Morales-Cruz (2021-2024)
  4. Ms. Julia Orrico (2020 – 2021): Julia’s first position after graduation was as a Product Development Engineer at Orthomerica in Orlando, FL.
  5. Mr. Charles Didier (2017 – 2019): Chuck continued his research in the NBSS Group as a Ph.D. student in Biomedical Sciences, UCF.

M.S. Non-Thesis Graduates

  1. Mr. Miguel Tirado (2018 – 2020): Miguel is currently teaching Science at Orange County Public Schools, Orlando, FL.
  2. Ms. An Nguyen (2016 – 2017): An’s first position after graduation was as a Product Development Engineer at LifeSouth in Gainesville, FL.

Post Doc and Research Associates Graduates

  1. Dr. Frank Sommerhage (2018 – 2021): Frank is currently CTO of Primordia BioSystems Inc., in Costa Mesa, CA and Orlando, FL and a Biological Sciences Professor at Keiser University in Orlando, FL
  2. Dr. Avra Kundu (2017 – 2020): Avra is currently Microelectronics Lab Manager in ECE Department at UCF in Orlando, FL.
  3. Dr. Syed Pasha (2019 – 2020): Syed’s first position after the post-doc at UCF was as a Process Engineer at Intel in Hillsborough, OR.
  4. Mr. David DeRoo (2018 – 2019): Dave is currently the CEO of Primordia BioSystems Inc., in Costa Mesa, CA and Orlando, FL.

Undergraduates and High School Students

Year Name Degree First Position After Graduation
2024 Mr. Isaac Johnson B.S. in Mechanical and Aerospace Engineering Engineer at Florida Space Institute
2024 Mr. Connor Edmonds B.S. in Mechanical and Aerospace Engineering Engineer at Northrop Grumman
2024 Mr. David Chand B.S. in Mechanical and Aerospace Engineering Junior in MAE at UCF
2023 Mr. Michael Meyers B.S. in Electrical Engineering Senior in ECE at UCF
2022 Ms. Aliyah Baksh B.S. in Biology, UCF Medical Student at the University of Miami, FL
2022 Ms. Maria Garcia-Chalbaud B.S. in Biomedical Engineering (REU), PUPR, San Juan, PR Senior in Biomedical Engineering, PUPR in San Juan, PR
2022 Ms. Rishika Khanna B.S. in Mechanical Engineering, IIT, Delhi, India Ph.D. student in Mechanical Engineering at the University of Texas, Austin, TX
2021 Mr. Adam Rozman B.S. in Mechanical Engineering, UCF Ph.D. student in Mechanical Engineering at the Boston University, Boston, MA
2021 Ms. Laboni Santra HS Diploma in Oviedo High School, Oviedo, FL B.S. student in Biological Engineering, MIT, Cambridge, MA
2021 Mr. Omar Cepeda B.S. in Biomedical Engineering (REU), PUPR, San Juan, PR M.S. Student in Nanotechnology, UCF
2021 Mr. Parker Arnett B.S. in Mechanical Engineering, UCF Quality Engineer, Olympia Pharma, Orlando, FL
2020 Mr. Nicholas Alban B.S. in Electrical Engineering, UCF
2019 Ms. Darina Khater B.S. in Aerospace Engineering, UCF Systems Engineer, Boeing, Cape Canaveral, FL
2019 Ms. Paola Morales Carvajal B.S. in Biomedical Engineering (REU), PUPR, San Juan, PR
2018 Mr. Tariq Ausaf B.S. in Electrical Engineering, UCF Law Student at the University of Florida, Gainesville, FL
2018 Ms. Crystal Nattoo B.S. in Electrical Engineering (REU),
University of Miami, Miami, FL
Ph.D. Student in Electrical Engineering,
Stanford University, Palo Alto, CA
2018 Ms. Sarah Springer B.S. in Biomedical Engineering (Senior Thesis), Hochschule Kaiserslautern, Germany M.S. Student in Biomedical Engineering, Heidelberg University, Germany
2018 Ms. Sandra Fremgen B.S. in Biomedical Engineering (Senior Thesis), Hochschule Kaiserslautern, Germany M.S. Student in Biomedical Engineering, Heidelberg University, Germany
2018 Ms. Valentina Parra Alvarez B.S. in Mechanical Engineering, UCF